9/7/2023 0 Comments Google profile tor eckhoff![]() ![]() ![]() Which is combination of hormone producing endocrine and nerveĬells, generally from the neural crest, neuroendocrine islets and Originating in the hormone producing cells of the endocrine system, Neuroendocrine tumors (NET) are neoplasms Neuroendocrine tumors, neuroendocrine cells This review will highlight the important points of accumulated knowledge covering the molecular aspects of the role of neuroendocrine cells, hormonal peptides, the reasons for ectopic hormone production in NET, neuropeptides and epigenetic regulation as well as the other challenging questions that require further understanding. NETs present a serious clinical challenge, as the survival rates remain low, and as these rare tumors are very difficult to study, novel approaches and therapies are required. In the majority of cases even surgical resection at that stage is unlikely to produce promising reusults. However, traditional conventional therapies such as radiation and chemotherapy are not effective. Clinical detection and diagnosis are reliable at the late stages when metastatic spread has occurred. These tumors develop in a number of organs, predominantly in the gastrointestinal and pulmonary systems. Neuroendocrine tumors (NETs) are a very heterogeneous group that are thought to originate from the cells of the endocrine and nervous systems. ![]()
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